Akutt og alvorlig allergisk reaksjon med symptomer som feber, utslett, opphovning, pustebesvær og blodtrykksfall. Anafylaktisk sjokk er livstruende om male ikke setter i gang med legemiddelbehandling i sort av antihistaminer og adrenalin. En ny omfattende meta-analyse viser at legemiddelet gir så liten smertelindring at det ikke er klinisk sig

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